T-Box 1 anticorps (AA 200-410)
Aperçu rapide pour T-Box 1 anticorps (AA 200-410) (ABIN5027059)
Antigène
Voir toutes T-Box 1 (TBX1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 200-410
-
Purification
- Protein A Chromatography
-
Immunogène
- A partial length recombinant Brachyury protein (amino acids 200-410) was used as the immunogen for this antibody.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB: 2-4 μg/mL
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 0.5 mg/mL
-
Buffer
- PBS containing 0.05 % BSA, PH 7.4
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
-
-
- T-Box 1 (TBX1)
-
Autre désignation
- Brachyury
-
Sujet
- Brachyury is a transcription factor encoded by T, a member of the T-box gene family, and required for posterior mesoderm formation and differentiation as well as for notochord development. It is expressed in all nascent mesoderm, in the embryo. Along with embryonic differentiation, it is downregulated, restricted into the notochord and the tail bud, and then lost, when notochordal cells are replaced by bone in the vertebral bodies and by the nucleus pulposus in the intervertebral discs. In the adult, brachyury expression has been found in chordoma, a malignant tumor which recapitulates notochord and derives from small collections of notochordal cells which may persist into the adult life.
-
Poids moléculaire
- 55 kDa
-
ID gène
- 6862
-
UniProt
- O15178
-
Pathways
- Retinoic Acid Receptor Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation
Antigène
-